Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034218 | 0.81 | ACHE (0.39) | PDE3BPDE3AHTR1AHTR2AHTR7 | |
| SCHEMBL6035141 | 0.80 | THRA (0.46) | PDE3BPDE3AHTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL4854986 | 0.80 | ACHE (0.39) | PDE3BPDE3AHTR1AHTR2AHTR7 | |
| SCHEMBL6034269 | 0.80 | ACHE (0.42) | PDE3BPDE3AACHE | |
| SCHEMBL27593268 | 0.80 | PDE3B (0.40) | PDE3BPDE3AHTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL4856597 | 0.80 | THRA (0.45) | PDE3BPDE3AHTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL4855018 | 0.79 | ACHE (0.43) | PDE3BPDE3AACHE | |
| SCHEMBL4859709 | 0.76 | PDE3B (0.44) | PDE3BPDE3AHTR1AHTR2AHTR7 | |
| SCHEMBL27611240 | 0.75 | TSHR (0.35) | HTR1AHTR2AHTR7DRD3DRD2 | |
| SCHEMBL6034243 | 0.72 | ACHE (0.40) | PDE3BPDE3AHTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589153-A | Prevention or treatment of urinary disorders | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-03-02 | — | — | CN | disclosed |