Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NMT2 | O60551 | 7/20 | 0.44 |
| ▸ | NMT1 | P30419 | 7/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617915 | 0.89 | EDNRA (0.65) | EDNRAKDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL3617244 | 0.85 | NPC1 (0.65) | KDM4ENPC1RAB9AHSD17B10NMT2 | |
| SCHEMBL6869797 | 0.79 | EDNRA (0.52) | EDNRAKDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL5584822 | 0.75 | EDNRA (0.51) | EDNRAKDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL7042865 | 0.74 | NMT2 (0.77) | EDNRANMT2NMT1ADRB2ADRB1 | |
| SCHEMBL6863214 | 0.73 | NMT2 (0.55) | KDM4ENPC1RAB9AHSD17B10NMT2 | |
| SCHEMBL6873768 | 0.72 | NPC1 (0.63) | EDNRAKDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL4000543 | 0.72 | ALDH1A1 (0.53) | KDM4ENPC1RAB9A | |
| SCHEMBL4950101 | 0.72 | EDNRA (0.47) | EDNRAKDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL28324547 | 0.71 | PARP15 (0.50) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1623537-A | Biaryl sulfonamides and its using method | WYETH CORP (US) | 2005-06-08 | — | — | CN | disclosed |