Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 13/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 9/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594401 | 0.84 | CYP11B1 (0.38) | CYP3A4MAPTKLKB1KLK1 | |
| SCHEMBL27612848 | 0.78 | CYP2A6 (0.61) | CYP2A6CYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL27594228 | 0.77 | — | — | |
| SCHEMBL27612961 | 0.76 | KDM4E (0.36) | CYP2A6ALDH1A1CYP1A2KDM4EMAPT | |
| SCHEMBL27613089 | 0.76 | MKNK1 (0.58) | DYRK1BCYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL12531203 | 0.75 | DYRK1A (0.62) | DYRK1ADYRK1BDYRK2CYP2A6CYP3A4 | |
| SCHEMBL6850770 | 0.74 | DYRK1A (0.53) | DYRK1ADYRK1BDYRK2CYP2A6CYP3A4 | |
| SCHEMBL6850779 | 0.74 | DYRK1A (0.53) | DYRK1ADYRK1BDYRK2CYP2A6CYP3A4 | |
| SCHEMBL6850775 | 0.74 | DYRK1A (0.53) | DYRK1ADYRK1BDYRK2CYP2A6CYP3A4 | |
| SCHEMBL6852565 | 0.71 | DYRK1A (0.57) | DYRK1ADYRK1BDYRK2CYP2A6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |