Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594282 | 0.84 | DYRK1A (0.51) | MAPTCYP3A4KLKB1KLK1 | |
| SCHEMBL27594228 | 0.80 | — | — | |
| SCHEMBL27612961 | 0.79 | KDM4E (0.36) | LMNAMAPTCYP19A1ERN1WNT3A | |
| SCHEMBL27612805 | 0.75 | PRKCI (0.50) | CYP11B1CYP11B2CYP3A4KLK1PRKACA | |
| SCHEMBL27612999 | 0.75 | CYP17A1 (0.42) | CYP11B1CYP11B2QDPRLMNAMAPT | |
| SCHEMBL18924665 | 0.71 | LMNA (0.44) | CYP11B1CYP11B2LMNAMAPTCYP3A4 | |
| SCHEMBL6850524 | 0.70 | QDPR (0.37) | CYP11B1CYP11B2QDPRLMNAMAPT | |
| SCHEMBL6850522 | 0.70 | QDPR (0.37) | CYP11B1CYP11B2QDPRLMNAMAPT | |
| SCHEMBL6850514 | 0.70 | QDPR (0.37) | CYP11B1CYP11B2QDPRLMNAMAPT | |
| SCHEMBL6852020 | 0.67 | MAPT (0.39) | CYP11B1CYP11B2QDPRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |