Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612793 | 0.82 | HDAC4 (0.40) | CYP2A6NPC1RAB9APIK3CDPI4KA | |
| SCHEMBL27612928 | 0.80 | HDAC4 (0.44) | DHODH | |
| SCHEMBL27613063 | 0.80 | HDAC4 (0.43) | CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL21745519 | 0.78 | KDM4E (0.50) | OPRD1CYP1A2KDM4ELMNAPOLB | |
| SCHEMBL27612839 | 0.76 | KDM4E (0.40) | CYP1A2KDM4ELMNAPOLBCCR1 | |
| SCHEMBL27594259 | 0.75 | CYP17A1 (0.42) | LMNACYP19A1CYP17A1CYP3A4 | |
| SCHEMBL1566968 | 0.73 | KDM4E (0.72) | CYP1A2KDM4ELMNAPOLBCCR1 | |
| SCHEMBL30989133 | 0.73 | KDM4E (0.72) | CYP1A2KDM4ELMNAPOLBCCR1 | |
| SCHEMBL30989132 | 0.73 | KDM4E (0.72) | CYP1A2KDM4ELMNAPOLBCCR1 | |
| SCHEMBL27594327 | 0.73 | KDM4E (0.51) | CYP1A2KDM4ELMNAPOLBCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |