Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 5/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594463 | 0.80 | OPRD1 (0.40) | DHODH | |
| SCHEMBL27612861 | 0.76 | HSD11B1 (0.34) | — | |
| SCHEMBL27612793 | 0.74 | HDAC4 (0.40) | HDAC4 | |
| SCHEMBL27594311 | 0.74 | CYP2A6 (0.47) | — | |
| SCHEMBL27594259 | 0.74 | CYP17A1 (0.42) | HDAC4 | |
| SCHEMBL27613063 | 0.73 | HDAC4 (0.43) | HDAC4 | |
| SCHEMBL27594291 | 0.71 | CYP1A2 (0.38) | — | |
| SCHEMBL8138043 | 0.69 | MAPT (0.56) | HDAC4DHODH | |
| SCHEMBL3458918 | 0.69 | NPY5R (0.47) | HDAC4DHODH | |
| SCHEMBL27612787 | 0.69 | HDAC4 (0.39) | HDAC4DHODHEP300WNT3APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |