Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594327 | 0.76 | KDM4E (0.51) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL28751291 | 0.76 | RAB9A (0.36) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL27594463 | 0.76 | OPRD1 (0.40) | KDM4ERAB9ANPC1LMNACCR1 | |
| SCHEMBL27612819 | 0.69 | KDM4E (0.42) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL27612864 | 0.69 | KDM4E (0.40) | KDM4ERAB9ANPC1MAPTLMNA | |
| SCHEMBL4470259 | 0.68 | KDM4E (0.55) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL27613084 | 0.68 | KDM4E (0.40) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL6851817 | 0.67 | KDM4E (0.42) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL6851822 | 0.67 | KDM4E (0.42) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL28753664 | 0.67 | KDM4E (0.42) | KDM4ERAB9ANPC1MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |