SCHEMBL2759490

SCHEMBL2759490

COc1cc(OC)c(C(=O)Oc2ccc(C(=O)Oc3ccc(-c4ccc(OC(=O)c5ccc(OC(=O)c6ccccc6OC)cc5)cc4)cc3)cc2)cc1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.56
NPSR1 Q6W5P4 2/20 0.56
HPGD P15428 1/20 0.56
XBP1 P17861 1/20 0.56
KMT2A Q03164 6/20 0.53
ESR1 P03372 2/20 0.52
MEN1 O00255 2/20 0.52
ALDH1A1 P00352 2/20 0.49
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP3A4 P08684 1/20 0.48
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ABCB1 P08183 1/20 0.47
ABCC1 P33527 1/20 0.47
SLC6A3 Q01959 1/20 0.46
TP53 P04637 1/20 0.46
GAA P10253 1/20 0.46
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824522 0.92 KMT2A (0.57) MAPTHPGDKMT2AALDH1A1CYP1A2
SCHEMBL13326246 0.88 KMT2A (0.53) MAPTNPSR1KMT2AMEN1ALDH1A1
SCHEMBL2734112 0.87 ALDH1A1 (0.47) MAPTNPSR1HPGDXBP1KMT2A
SCHEMBL14435920 0.87 KMT2A (0.52) MAPTKMT2AESR1MEN1ALDH1A1
SCHEMBL14539458 0.87 KMT2A (0.52) MAPTKMT2AESR1MEN1ALDH1A1
SCHEMBL9905844 0.86 ALDH1A1 (0.56) MAPTNPSR1HPGDXBP1KMT2A
SCHEMBL9905881 0.86 ALDH1A1 (0.61) MAPTNPSR1HPGDXBP1KMT2A
SCHEMBL9683161 0.85 MAPT (0.67) MAPTNPSR1HPGDXBP1KMT2A
SCHEMBL14026519 0.84 KMT2A (0.60) MAPTHPGDKMT2AMEN1ALDH1A1
SCHEMBL2732330 0.83 SMPD1 (0.51) HPGDKMT2AMEN1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8313814-B2 Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-11-20 US disclosed
US-8313814-B2 Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-11-20 US disclosed
US-8247041-B2 Cellulose acylate film FUJIFILM CORPORATION (JP) 2012-08-21 US disclosed
US-8247041-B2 Cellulose acylate film FUJIFILM CORPORATION (JP) 2012-08-21 US disclosed
US-8197726-B2 Cellulose acylate film and method for producing same FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8197726-B2 Cellulose acylate film and method for producing same FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7981489-B2 Optical compensation sheet and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-7981489-B2 Optical compensation sheet and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-7951430-B2 Cellulose acylate film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-05-31 US disclosed
US-20080165312-A1 Optical Compensation Sheet and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-10 US disclosed
US-20080111954-A1 Cellulose Acylate Film And Method For Producing Same FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed
US-20080111954-A1 Cellulose Acylate Film And Method For Producing Same FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed
US-20080113118-A1 cellulose ester films produced by melt-casting, having microstructure projections and depressions, used as polarizing layers and substrates for optically-compensatory films for liquid crystal display plates and antireflection films, which reduces distortion of displays FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed
US-20080113118-A1 cellulose ester films produced by melt-casting, having microstructure projections and depressions, used as polarizing layers and substrates for optically-compensatory films for liquid crystal display plates and antireflection films, which reduces distortion of displays FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed
WO-2007086538-A1 RETARDATION PLATE, POLARIZER PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPOTATION (JP) 2007-08-02 WO disclosed
US-20070077373-A1 Polymer film and polarizing plate and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070077373-A1 Polymer film and polarizing plate and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 US disclosed