Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | XBP1 | P17861 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | ACR | P10323 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547850 | 0.91 | KMT2A (0.68) | MAPTHPGDXBP1NPSR1KMT2A | |
| SCHEMBL4389475 | 0.85 | NPSR1 (0.72) | MAPTHPGDXBP1NPSR1KMT2A | |
| SCHEMBL2149614 | 0.85 | MAPT (0.71) | MAPTHPGDXBP1NPSR1KMT2A | |
| SCHEMBL2759490 | 0.85 | MAPT (0.56) | MAPTHPGDXBP1NPSR1KMT2A | |
| SCHEMBL5706030 | 0.84 | SLC6A3 (0.77) | MAPTKMT2AESR1MEN1ALDH1A1 | |
| SCHEMBL9010699 | 0.84 | KMT2A (0.72) | MAPTHPGDXBP1NPSR1KMT2A | |
| SCHEMBL10894177 | 0.84 | MAPT (0.62) | MAPTHPGDXBP1NPSR1KMT2A | |
| SCHEMBL21159215 | 0.83 | KMT2A (0.67) | MAPTKMT2AESR1ALDH1A1LMNA | |
| SCHEMBL16429579 | 0.83 | CES2 (0.69) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL18088853 | 0.83 | KMT2A (0.66) | MAPTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0354347-A2 | Liquid crystal compounds,their manufacture as modifiers for polycarbonates,polyestercarbonates and polyesters | BAYER AG (DE) | 1990-02-14 | — | — | EP | disclosed |