Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28712193 | 0.96 | EGFR (0.64) | EGFRERBB2LMNACES2CES1 | |
| SCHEMBL27951879 | 0.94 | LMNA (0.55) | EGFRERBB2LMNACES2CES1 | |
| SCHEMBL3451753 | 0.93 | LMNA (0.56) | EGFRERBB2LMNACES2CES1 | |
| SCHEMBL28188561 | 0.92 | EGFR (0.56) | EGFRERBB2LMNAKMT2AMEN1 | |
| SCHEMBL27473758 | 0.90 | EGFR (0.58) | EGFRERBB2LMNACES2CES1 | |
| SCHEMBL1820340 | 0.88 | MTNR1B (0.55) | EGFRERBB2LMNACES2CES1 | |
| SCHEMBL12742253 | 0.86 | LMNA (0.58) | EGFRERBB2LMNACES2CES1 | |
| SCHEMBL8386903 | 0.86 | EGFR (0.52) | EGFRERBB2LMNACES2CES1 | |
| SCHEMBL10407331 | 0.86 | KMT2A (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL17138133 | 0.86 | LMNA (0.49) | EGFRERBB2LMNAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100408614-C | Method for producing polycarbonate | GEN ELECTRIC (US) | 2008-08-06 | — | — | CN | disclosed |
| CN-1561356-A | Method for producing polycarbonate | GEN ELECTRIC (US) | 2005-01-05 | — | — | CN | disclosed |