Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.47 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.43 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690904 | 0.81 | KDM6B (0.46) | KDM6BKDM4CHCAR3MAPTKDM4E | |
| SCHEMBL29033346 | 0.81 | KDM6B (0.57) | KDM6BKDM4CHCAR3CISD1PLK1 | |
| SCHEMBL27498211 | 0.78 | POLB (0.54) | GAAMAPTLMNAHPGDKDM4E | |
| SCHEMBL15934301 | 0.77 | KDM6B (0.39) | KDM6BKDM4CHCAR3GUCY1A1GUCY1B1 | |
| SCHEMBL27736211 | 0.76 | KDM6B (0.52) | KDM6BKDM4CHCAR3CISD1PLK1 | |
| SCHEMBL14620215 | 0.76 | IDO1 (0.49) | KDM6BKDM4CHCAR3CISD1GAA | |
| SCHEMBL28114974 | 0.76 | KDM6B (0.49) | KDM6BKDM4CHCAR3CISD1PLK1 | |
| SCHEMBL27756887 | 0.75 | PLK1 (0.52) | KDM6BKDM4CHCAR3CISD1PLK1 | |
| SCHEMBL15412099 | 0.75 | HCAR3 (0.64) | KDM6BKDM4CHCAR3PLK1GAA | |
| SCHEMBL27542122 | 0.75 | HCAR3 (0.41) | KDM6BKDM4CHCAR3CISD1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1623992-A | Novel medicine of non peptide like angiotensin II receptor antagonism agent, their preparation and application | UNIV BEIJING NORMAL (CN) | 2005-06-08 | — | — | CN | disclosed |