Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 2/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
| ▸ | PLK1 | P53350 | 4/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27568535 | 0.91 | CISD1 (0.45) | KDM6BKDM4CPLK1HCAR3CNR1 | |
| SCHEMBL27736211 | 0.89 | KDM6B (0.52) | KDM6BKDM4CPLK1HCAR3CNR1 | |
| SCHEMBL27756887 | 0.88 | PLK1 (0.52) | KDM6BKDM4CPLK1HCAR3CNR1 | |
| SCHEMBL29033346 | 0.84 | KDM6B (0.57) | KDM6BKDM4CPLK1HCAR3CNR1 | |
| SCHEMBL2382976 | 0.84 | CNR2 (0.50) | KDM6BKDM4CPLK1HCAR3CNR1 | |
| SCHEMBL23748664 | 0.81 | CNR2 (0.50) | KDM6BKDM4CPLK1CNR1CNR2 | |
| SCHEMBL11247334 | 0.80 | PLK1 (0.51) | KDM6BKDM4CPLK1HCAR3CNR1 | |
| SCHEMBL7489220 | 0.80 | HCAR3 (0.64) | PLK1HCAR3 | |
| SCHEMBL5136114 | 0.79 | PLK1 (0.51) | KDM6BKDM4CPLK1CNR1CNR2 | |
| SCHEMBL28110422 | 0.78 | PLK1 (0.67) | KDM6BKDM4CPLK1HCAR3CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243105-A | Methylene-bridged 1,8 naphthyridines part and copper (I) coordination compound, preparation method and application | 红河学院 | 2016-12-21 | — | — | CN | disclosed |