Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595642 | 0.85 | ATM (0.36) | ATMHSD17B10GPR119MAPK1GAA | |
| SCHEMBL4873641 | 0.84 | F2 (0.34) | HSD17B10NAMPT | |
| SCHEMBL4870547 | 0.82 | ALDH1A1 (0.33) | ATMHSD17B10MAPK1GAATSHR | |
| SCHEMBL27577587 | 0.81 | HSD17B10 (0.39) | ATMHSD17B10GPR119GAATSHR | |
| SCHEMBL27595651 | 0.80 | HSD17B10 (0.38) | ATMHSD17B10GPR119GAATSHR | |
| SCHEMBL27492229 | 0.79 | — | — | |
| SCHEMBL27491173 | 0.75 | CYP2D6 (0.37) | — | |
| SCHEMBL4875506 | 0.73 | ALDH1A1 (0.35) | ALDH1A1NAMPTMEN1KMT2A | |
| SCHEMBL4863405 | 0.72 | SMN1; SMN2 (0.32) | SMN1; SMN2NAMPTCNR2 | |
| SCHEMBL27595646 | 0.71 | CCR5 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1430610-A | Substituted 1-aminoalkyllactam compounds and their use as muscarinic receptor antagonists | HOFFMANN LA ROCHE (CH) | 2003-07-16 | — | — | CN | disclosed |