Flavanone

Flavanone

SCHEMBL27595693

O=C1CC(c2ccccc2)Oc2ccccc21.Oc1ccccc1

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 3/20 0.88
MAPT P10636 3/20 0.88
NPC1 O15118 2/20 0.88
RAB9A P51151 2/20 0.88
CYP3A4 P08684 2/20 0.88
MAPK1 P28482 1/20 0.88
MAOB P27338 6/20 0.84
CYP19A1 P11511 5/20 0.84
AR P10275 3/20 0.84
HSD17B10 Q99714 2/20 0.84
KDM4E B2RXH2 1/20 0.84
MAOA P21397 1/20 0.71
PSMB5 P28074 1/20 0.71
HSD11B1 P28845 1/20 0.64
AKR1C3 P42330 1/20 0.64
TUBB4A P04350 1/20 0.64
TUBB P07437 1/20 0.64
YES1 P07947 1/20 0.64
TUBA3C P0DPH7 1/20 0.64
TUBA1B P68363 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4'-Hydroxy-Flavanone SCHEMBL2283830 0.94 ADORA3 (1.00) ADORA3MAPTNPC1RAB9ACYP3A4
4'-Hydroxy-Flavanone SCHEMBL10362253 0.94 ADORA3 (1.00) ADORA3MAPTNPC1RAB9ACYP3A4
4'-Hydroxy-Flavanone SCHEMBL2283823 0.94 ADORA3 (1.00) ADORA3MAPTNPC1RAB9ACYP3A4
Flavanone SCHEMBL12189591 0.92 MAOB (1.00) ADORA3MAPTNPC1RAB9ACYP3A4
Flavanone SCHEMBL12660199 0.92 MAOB (1.00) ADORA3MAPTNPC1RAB9ACYP3A4
Flavanone SCHEMBL29470801 0.92 MAOB (1.00) ADORA3MAPTNPC1RAB9ACYP3A4
Flavanone SCHEMBL29843289 0.92 MAOB (1.00) ADORA3MAPTNPC1RAB9ACYP3A4
Flavanone SCHEMBL19745 0.92 MAOB (1.00) ADORA3MAPTNPC1RAB9ACYP3A4
Flavanone SCHEMBL27610362 0.90 MAOB (0.90) ADORA3MAPTNPC1RAB9ACYP3A4
Flavanone SCHEMBL11733114 0.90 MAOB (0.96) ADORA3MAPTNPC1RAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100469893-C Process for producing glycosyl transfer product EZAKI GLICO CO (JP) 2009-03-18 CN disclosed
CN-1434871-A Process for producing glycosyl transfer product EZAKI GLICO CO (JP) 2003-08-06 CN disclosed