SCHEMBL27595698

SCHEMBL27595698

CCOC(=O)c1c(N)ccc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.53
RAB9A P51151 3/20 0.53
NPC1 O15118 2/20 0.53
ALDH1A1 P00352 4/20 0.53
HSD17B10 Q99714 2/20 0.53
CDC25B P30305 2/20 0.52
KDM4E B2RXH2 5/20 0.51
TP53 P04637 1/20 0.51
MAPK1 P28482 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CDC25A P30304 1/20 0.49
CDC25C P30307 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
GAA P10253 2/20 0.48
GLA P06280 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27960997 0.87 KMT2A (0.45) KMT2ARAB9ANPC1ALDH1A1HSD17B10
SCHEMBL277281 0.84 KMT2A (0.57) KMT2ARAB9ANPC1ALDH1A1CDC25B
SCHEMBL10051639 0.83 CDC25B (0.54) KMT2ARAB9ANPC1ALDH1A1CDC25B
SCHEMBL29856064 0.83 CDC25B (0.61) KMT2ARAB9ANPC1ALDH1A1HSD17B10
SCHEMBL560585 0.83 CDC25B (0.61) KMT2ARAB9ANPC1ALDH1A1HSD17B10
SCHEMBL28257925 0.83 CA12 (0.64) KMT2ANPC1ALDH1A1CDC25BKDM4E
SCHEMBL3978725 0.82 NCEH1 (0.57) KMT2AALDH1A1HSD17B10KDM4EMAPK1
SCHEMBL9464255 0.82 GAA (0.55) KMT2AALDH1A1HSD17B10KDM4EMAPK1
SCHEMBL6161826 0.81 KMT2A (0.43) KMT2ARAB9ANPC1ALDH1A1HSD17B10
SCHEMBL27553344 0.81 CDC25B (0.52) KMT2ARAB9ANPC1ALDH1A1CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102316871-B [1,2,4]thiadiazine 1,1-dioxide compounds ANADYS PHARMACEUTICALS INC 2014-06-04 CN disclosed
CN-1483064-A Use of copper complexes of disazo dyes for dyeing natural and synthetic material �������⻯ѧƷ�ع����޹�˾ 2004-03-17 CN disclosed