SCHEMBL9464255

SCHEMBL9464255

CCOC(=O)c1c(N)ccc2ccc(O)cc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.55
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTT P42858 1/20 0.50
GPR55 Q9Y2T6 1/20 0.50
LMNA P02545 4/20 0.49
KDM4E B2RXH2 3/20 0.49
HSD17B10 Q99714 2/20 0.49
MAPT P10636 2/20 0.49
MAPK10 P53779 1/20 0.49
CA12 O43570 4/20 0.49
CA1 P00915 4/20 0.49
CA2 P00918 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9621587 0.89 ALDH1A1 (0.49) GAAMEN1KMT2AALDH1A1HPGD
SCHEMBL10341612 0.84 CA12 (0.46) GAAALDH1A1HPGDSMN1; SMN2CYP1A2
SCHEMBL27595698 0.82 KMT2A (0.53) GAAMEN1KMT2AALDH1A1HPGD
SCHEMBL10763286 0.80 HSP90AB1 (0.45) GAAMEN1KMT2ACA9ESR1
SCHEMBL10480212 0.78 MCL1 (0.42) GAAMEN1KMT2AALDH1A1HPGD
SCHEMBL10743287 0.76 CA12 (0.70) GAAMEN1KMT2AALDH1A1HPGD
Hydrochloric Acid SCHEMBL28066278 0.75 CA12 (0.68) GAAMEN1KMT2AALDH1A1HPGD
SCHEMBL8442287 0.74 CA12 (0.65) GAAMEN1KMT2AALDH1A1HPGD
SCHEMBL28772584 0.73 CA12 (0.70) GAAMEN1KMT2AALDH1A1CYP1A2
SCHEMBL15214245 0.73 CA12 (0.58) GAAALDH1A1HPGDSMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5204453-A Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
US-4704133-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1987-11-03 US disclosed
US-4680385-A Metal dye complexes containing an azo or azomethine dye and a colorless ligand with the C═N--N═C group CIBA-GEIGY CORPORATION (US) 1987-07-14 US disclosed
US-4678851-A FIBER-RACTIVE CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
EP-0100297-B1 BIS-1:2-CHROMIUM COMPLEXES OF DISAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-01-08 EP disclosed
EP-0048693-B1 DISAZO DYESTUFFS, METAL COMPLEXES THEREOF, THEIR PREPARATION AND USE CIBA-GEIGY AG (CH) 1986-01-08 EP disclosed
US-4340536-A Chrome-complex dyes and the production and use thereof CIBA-GEIGY CORPORATION (US) 1982-07-20 US disclosed