Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
| ▸ | CDC25C | P30307 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856064 | 0.85 | CDC25B (0.61) | KMT2AKDM4EMAPK1L3MBTL1CDC25B | |
| SCHEMBL10051639 | 0.85 | CDC25B (0.54) | KMT2AKDM4EMAPK1L3MBTL1CDC25B | |
| SCHEMBL560585 | 0.85 | CDC25B (0.61) | KMT2AKDM4EMAPK1L3MBTL1CDC25B | |
| SCHEMBL28257925 | 0.85 | CA12 (0.64) | KMT2AKDM4EMAPK1L3MBTL1CDC25B | |
| SCHEMBL27595698 | 0.84 | KMT2A (0.53) | KMT2AKDM4EMAPK1L3MBTL1CDC25B | |
| Butane SCHEMBL7938601 | 0.84 | CDC25B (0.60) | KMT2AKDM4EMAPK1L3MBTL1CDC25B | |
| SCHEMBL27553344 | 0.84 | CDC25B (0.52) | KMT2AKDM4EMAPK1L3MBTL1CDC25B | |
| SCHEMBL1648076 | 0.83 | NCEH1 (0.59) | KMT2AKDM4EMAPK1CA12CA1 | |
| SCHEMBL5835576 | 0.83 | CA12 (0.55) | KMT2AKDM4EMAPK1L3MBTL1CDC25B | |
| SCHEMBL11056026 | 0.83 | CDC25B (0.55) | KMT2AKDM4EMAPK1L3MBTL1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134005-B2 | Preparation and use of magnesium amides | Ludwig-Maximilians-Universitat München (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20100144516-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | MLX, GLRX3, SFXN3 | KMT2A 1480/4885KDM4E 3049/4885MAPK1 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.