Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615506 | 0.87 | CYP2C19 (0.48) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL27838486 | 0.86 | MAPT (0.46) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL2283147 | 0.86 | MAPT (0.48) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL29118559 | 0.86 | KMT2A (0.48) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL16028069 | 0.84 | MAPT (0.47) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL340104 | 0.84 | CYP2C19 (0.46) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL1742568 | 0.84 | CYP2C19 (0.46) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL10518614 | 0.84 | MAPT (0.47) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL7619909 | 0.83 | SLC6A2 (0.48) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL29118554 | 0.83 | MAPT (0.46) | MAPTKMT2ACYP2C19HIF1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1481369-A | Substituted phenyluracils compound | �ݶ�ũ�����ѧ�ɷݹ�˾ | 2004-03-10 | — | — | CN | disclosed |
| CN-86104807-A | Carbonylation method | — | 1987-02-25 | — | — | CN | disclosed |