Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667978 | 0.90 | NR3C2 (0.41) | SLC6A2TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL29118559 | 0.83 | KMT2A (0.48) | TAAR1CYP1A2CYP3A4RECQLMAPK1 | |
| SCHEMBL27596019 | 0.83 | MAPT (0.48) | TAAR1CYP1A2CYP3A4RECQLMAPK1 | |
| SCHEMBL2283147 | 0.83 | MAPT (0.48) | TAAR1CYP1A2MAPTKMT2ACYP2C19 | |
| SCHEMBL16028069 | 0.81 | MAPT (0.47) | TAAR1CYP1A2CYP3A4RECQLMAPK1 | |
| SCHEMBL10518614 | 0.81 | MAPT (0.47) | TAAR1CYP1A2CYP3A4RECQLMAPK1 | |
| SCHEMBL3656311 | 0.81 | SMN1; SMN2 (0.48) | SLC6A2TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL9278784 | 0.81 | HIF1A (0.48) | SLC6A2TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL12390094 | 0.81 | KCNH2 (0.44) | SLC6A2TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL29118554 | 0.80 | MAPT (0.46) | TAAR1CYP1A2CYP3A4RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437012-B1 | Low-swelling, macroporous polymer-supported reagents for organic synthesis and purification | AGILENT TECHNOLOGIES, INC. | 2002-08-20 | — | — | US | disclosed |