Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647321 | 0.86 | CTSL (0.69) | CTSLATMMETTL3ALDH1A1LMNA | |
| SCHEMBL27999578 | 0.84 | CTSL (0.70) | CTSLATMMETTL3ALDH1A1LMNA | |
| SCHEMBL8426264 | 0.83 | CTSL (0.66) | CTSLATMMETTL3ALDH1A1LMNA | |
| SCHEMBL8426262 | 0.83 | CTSL (0.66) | CTSLATMMETTL3ALDH1A1LMNA | |
| SCHEMBL2675573 | 0.82 | CTSL (0.73) | CTSLATMMETTL3ALDH1A1LMNA | |
| SCHEMBL941203 | 0.82 | CTSL (0.68) | CTSLATMMETTL3SMN1; SMN2CTSB | |
| SCHEMBL6229384 | 0.82 | CTSL (0.68) | CTSLATMMETTL3ALDH1A1LMNA | |
| SCHEMBL25408895 | 0.81 | CTSL (0.66) | CTSLATMMETTL3ALDH1A1LMNA | |
| SCHEMBL27647421 | 0.81 | CTSL (0.71) | CTSLATMMETTL3ALDH1A1LMNA | |
| SCHEMBL27950773 | 0.81 | CTSL (1.00) | CTSLATMMETTL3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100484928-C | thiadiazoline derivatives | KYOWA HAKKO KOGYO KK FUJI PHOT (JP) | 2009-05-06 | — | — | CN | disclosed |
| CN-1617864-A | thiadiazoline derivatives | KYOWA HAKKO KOGYO KK (JP) | 2005-05-18 | — | — | CN | disclosed |