Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426264 | 1.00 | CTSL (0.66) | CTSLGAAMAPTL3MBTL1CTSB | |
| SCHEMBL27647321 | 0.90 | CTSL (0.69) | CTSLGAAMAPTL3MBTL1CTSB | |
| SCHEMBL8428406 | 0.88 | CTSL (0.51) | CTSLGAAMAPTL3MBTL1CTSB | |
| SCHEMBL8428101 | 0.88 | CTSL (0.51) | CTSLCTSB | |
| SCHEMBL8428098 | 0.88 | CTSL (0.51) | CTSLCTSB | |
| SCHEMBL8428408 | 0.88 | CTSL (0.51) | CTSLGAAMAPTL3MBTL1CTSB | |
| SCHEMBL8426077 | 0.87 | CTSL (0.55) | CTSLCTSB | |
| SCHEMBL8426079 | 0.87 | CTSL (0.55) | CTSLCTSB | |
| SCHEMBL941477 | 0.84 | CTSL (0.66) | CTSLGAAMAPTL3MBTL1CTSB | |
| SCHEMBL941478 | 0.84 | CTSL (0.66) | CTSLGAAMAPTL3MBTL1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008362-A | TREATING ATHEROSCLEROSIS IN MAMMALS | WYETH | 1999-12-28 | — | — | US | claimed |
| US-6008362-A | TREATING ATHEROSCLEROSIS IN MAMMALS | WYETH | 1999-12-28 | — | — | US | disclosed |
| WO-1998057928-A1 | ELEVATION OF HDL CHOLESTEROL BY 2-(4-CHLORO -1-ARYL-BUTYLIDENE) -HYDRAZINECARBOTHIOAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |