Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940759 | 0.81 | CYP1A2 (1.00) | CYP1A2CTSLATMMETTL3SMN1; SMN2 | |
| SCHEMBL942362 | 0.81 | CYP1A2 (1.00) | CYP1A2CTSLATMMETTL3SMN1; SMN2 | |
| SCHEMBL3072018 | 0.74 | TSHR (0.39) | CYP1A2ATMGAAKMT2ASMN1; SMN2 | |
| SCHEMBL17988364 | 0.74 | TSHR (0.39) | CYP1A2ATMGAAKMT2ASMN1; SMN2 | |
| SCHEMBL941203 | 0.73 | CTSL (0.68) | CTSLATMMETTL3SMN1; SMN2 | |
| SCHEMBL28751451 | 0.70 | CTSL (0.50) | CTSLATMMETTL3 | |
| SCHEMBL941727 | 0.70 | HTT (0.52) | CTSLATMMETTL3ALDH1A1LMNA | |
| SCHEMBL27596093 | 0.69 | ALDH1A1 (0.50) | CTSLALDH1A1LMNAGAAHTT | |
| SCHEMBL27596097 | 0.69 | CTSL (0.68) | CTSLALDH1A1LMNAHTTKMT2A | |
| SCHEMBL5701316 | 0.68 | TOP2A (0.51) | LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101787000-B | M-stage kinesin inhibitor | KYOWA HAKKO KOGYO KK | 2011-08-03 | — | — | CN | disclosed |
| CN-101787000-A | M-stage kinesin inhibitor | KYOWA HAKKO KOGYO KK | 2010-07-28 | — | — | CN | disclosed |
| CN-1774428-B | M-phase kinesin inhibitors | KYOWA HAKKO KOGYO KK | 2010-06-16 | — | — | CN | disclosed |
| CN-100484928-C | thiadiazoline derivatives | KYOWA HAKKO KOGYO KK FUJI PHOT (JP) | 2009-05-06 | — | — | CN | disclosed |
| CN-1774428-A | M-phase kinesin inhibitors | KYOWA HAKKO KOGYO KK (JP) | 2006-05-17 | — | — | CN | disclosed |
| CN-1617864-A | thiadiazoline derivatives | KYOWA HAKKO KOGYO KK (JP) | 2005-05-18 | — | — | CN | disclosed |