Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.42 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28749394 | 0.90 | ERN1 (0.44) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL5859920 | 0.82 | ERN1 (0.48) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL5859062 | 0.78 | BCHE (0.42) | ERN1CA1CA2CNR2GPR55 | |
| SCHEMBL28749393 | 0.77 | ALDH1A1 (0.39) | ERN1CA1CA2CNR2GPR55 | |
| SCHEMBL27578054 | 0.76 | CNR2 (0.35) | CNR1CNR2GPR55ALDH1A1HTT | |
| SCHEMBL6536167 | 0.76 | ERN1 (0.53) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL27596110 | 0.75 | KDM4E (0.45) | CNR2GPR55ALDH1A1LMNAHPGD | |
| SCHEMBL6095843 | 0.75 | L3MBTL1 (0.46) | ALDH1A1HPGDHTTSMN1; SMN2HTR1A | |
| SCHEMBL5859253 | 0.74 | CA1 (0.44) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL6096037 | 0.72 | TUBB1 (0.48) | ERN1CA2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1460097-A | NF-kB inhibitor containing substituted benzoic acid derivative as active ingredient | DAIICHI SUNTORY SEIYAKU CO LTD (JP) | 2003-12-03 | — | — | CN | disclosed |