Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706653 | 0.96 | ELANE (0.37) | CYP2C19HIF1ATDP1L3MBTL1ELANE | |
| SCHEMBL27596163 | 0.90 | TDP1 (0.41) | CYP2C19HIF1ATDP1FFAR1CPT2 | |
| SCHEMBL6694821 | 0.85 | ELANE (0.35) | CYP2C19HIF1ATDP1FFAR1CPT2 | |
| SCHEMBL6510734 | 0.84 | ELANE (0.38) | L3MBTL1ELANEATMCYP19A1HTT | |
| SCHEMBL6690011 | 0.84 | KMT2A (0.39) | TDP1L3MBTL1ELANEATMCYP19A1 | |
| SCHEMBL27596154 | 0.83 | KMT2A (0.36) | FFAR1L3MBTL1ELANEATMCYP19A1 | |
| SCHEMBL9427528 | 0.83 | CYP2C19 (0.47) | CYP2C19HIF1ATDP1FFAR1CPT2 | |
| SCHEMBL6503923 | 0.80 | FFAR1 (0.54) | CYP2C19HIF1ATDP1FFAR1CPT2 | |
| SCHEMBL6699922 | 0.79 | ELANE (0.38) | L3MBTL1ELANEATMCYP19A1PPARA | |
| SCHEMBL6697288 | 0.77 | ALDH1A1 (0.46) | TDP1L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1479721-A | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol therapy and related applications | ͨ��ҽ�ƹ�˾ | 2004-03-03 | — | — | CN | disclosed |