Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690011 | 0.96 | KMT2A (0.39) | KMT2APRSS1PRSS2PRSS3EGFR | |
| SCHEMBL6706653 | 0.84 | ELANE (0.37) | KMT2APRSS1PRSS2PRSS3EGFR | |
| SCHEMBL27596177 | 0.83 | CYP2C19 (0.36) | KMT2AEGFRERBB2ALDH1A1MAPT | |
| SCHEMBL6697864 | 0.80 | NAALAD2 (0.37) | KMT2AALDH1A1LMNAHSD17B10ESR1 | |
| SCHEMBL6694592 | 0.78 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPTHTTLMNA | |
| SCHEMBL3287014 | 0.78 | KMT2A (0.43) | KMT2APRSS1PRSS2PRSS3EGFR | |
| SCHEMBL28358799 | 0.76 | KMT2A (0.44) | KMT2APRSS1PRSS2PRSS3EGFR | |
| SCHEMBL6509256 | 0.75 | ELANE (0.47) | PRSS1MAPTATML3MBTL1ELANE | |
| SCHEMBL13053709 | 0.74 | L3MBTL1 (0.41) | KMT2APRSS1PRSS2PRSS3EGFR | |
| SCHEMBL6346152 | 0.74 | KMT2A (0.40) | KMT2APRSS1PRSS2PRSS3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1479721-A | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol therapy and related applications | ͨ��ҽ�ƹ�˾ | 2004-03-03 | — | — | CN | disclosed |