Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14421685 | 0.85 | NPY5R (0.55) | NPY5RCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27614917 | 0.83 | F2 (0.37) | ALDH1A1KDM4EHSD17B10MAPK1F2 | |
| SCHEMBL5563864 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4ENPSR1KMT2ANPC1 | |
| SCHEMBL27614970 | 0.78 | TOP2A (0.43) | ALDH1A1KDM4EHSD17B10MAPK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5569140 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4ENPSR1KMT2ANPC1 | |
| SCHEMBL5563859 | 0.77 | PIK3CG (0.47) | ALDH1A1KDM4EMAPK1CYP3A4NPSR1 | |
| SCHEMBL5564379 | 0.77 | NPY5R (0.44) | NPY5R | |
| SCHEMBL5567784 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPSR1 | |
| SCHEMBL27614967 | 0.76 | NPC1 (0.40) | ALDH1A1KDM4EHSD17B10MAPK1CYP2C9 | |
| SCHEMBL5567835 | 0.76 | GAA (0.47) | ALDH1A1KDM4EHSD17B10MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100363362-C | Thiazole derivatives as NPY receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | CN | disclosed |
| CN-1639158-A | Thiazole derivatives as NPY receptor antagonists | HOFFMANN LA ROCHE (CH) | 2005-07-13 | — | — | CN | disclosed |