Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746237 | 0.81 | GPBAR1 (0.52) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL19051436 | 0.81 | GPBAR1 (0.52) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL17449881 | 0.80 | RAB9A (0.62) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL5254704 | 0.79 | NPC1 (0.46) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL4439987 | 0.79 | CTSS (0.50) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL4445412 | 0.78 | NPC1 (0.48) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL26613375 | 0.76 | AR (0.53) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL29746283 | 0.76 | AR (0.53) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL18126526 | 0.75 | NPC1 (0.43) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL4216248 | 0.75 | RAB9A (0.56) | NPC1RAB9AARCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1520702-B | Electroluminescent irisium compounds with fluorinated phenylpyridines, phenylpyridines and phenylquinolines and device made with such compounds | DU PONT | 2010-05-26 | — | — | CN | disclosed |
| CN-100438123-C | Electroluminescent iridium compounds containing fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with the compounds | DU PONT (US) | 2008-11-26 | — | — | CN | disclosed |
| CN-1520702-A | Electroluminescent irisium compounds with fluorinated phenylpyridines, phenylpyridines and phenylquinolines and device made with such compounds | ��Ļ���Ű˾ | 2004-08-11 | — | — | CN | disclosed |
| CN-1449640-A | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such | DU PONT (US) | 2003-10-15 | — | — | CN | disclosed |