Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843505 | 0.92 | DGAT1 (0.34) | PDE10ADGAT1KLKB1 | |
| SCHEMBL4760581 | 0.82 | DGAT1 (0.34) | PDE10ADGAT1KLKB1 | |
| SCHEMBL1767786 | 0.79 | PDE10A (0.41) | PDE10ADGAT1KLKB1 | |
| SCHEMBL25129933 | 0.78 | PDE10A (0.36) | PDE10ADGAT1KLKB1 | |
| SCHEMBL2072306 | 0.78 | DUT (0.39) | PDE10ADGAT1 | |
| SCHEMBL4428338 | 0.78 | DGAT1 (0.36) | PDE10ADGAT1KLKB1 | |
| SCHEMBL31021830 | 0.78 | DGAT1 (0.41) | PDE10ADGAT1KLKB1 | |
| SCHEMBL614260 | 0.78 | DGAT1 (0.44) | PDE10ADGAT1KLKB1 | |
| SCHEMBL25130230 | 0.76 | DGAT1 (0.33) | PDE10ADGAT1KLKB1 | |
| SCHEMBL31628936 | 0.75 | DGAT1 (0.35) | PDE10ADGAT1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1457339-A | Chemokine receptor binding heterocyclic compounds | ANORMED INC (CA) | 2003-11-19 | — | — | CN | disclosed |