Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.59 |
| ▸ | CES1 | P23141 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7007737 | 1.00 | FAAH (0.59) | FAAHCES1MEN1KMT2ACES2 | |
| Palmitamide SCHEMBL17079324 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL17079411 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Nonanoamide SCHEMBL28509070 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL17079322 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL17079471 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Tetradecanamide SCHEMBL17079414 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Heptanamide SCHEMBL28390014 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL30164282 | 0.93 | FAAH (0.50) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL27386746 | 0.93 | FAAH (0.50) | FAAHCES1MEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119564878-A | Bioactive substance conjugate, preparation method and application thereof | 苏州宜联生物医药有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-115279417-B | Bioactive substance conjugate, preparation method and application thereof | 苏州宜联生物医药有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-110914240-B | Norbornenone compounds releasing carbon monoxide | 奥塔哥创新有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-115960111-A | Antibody-drug conjugates | 第一三共株式会社 | 2023-04-14 | — | — | CN | disclosed |
| CN-115279417-A | Bioactive substance conjugate and preparation method and application thereof | 苏州宜联生物医药有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-110891951-A | Compound (I) | 谢菲尔德大学 | 2020-03-17 | — | — | CN | disclosed |
| CN-109081871-A | Antibody-drug conjugates | 第三共株式会社 | 2018-12-25 | — | — | CN | disclosed |
| CN-108650882-A | Composition for the cancer for treating expression IGF-1R | 皮埃尔法布雷医药公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-104755494-B | antibody-drug conjugates | 第三共株式会社 | 2018-09-07 | — | — | CN | disclosed |
| CN-108025086-A | Antibody-active agent conjugates (ADC) of KSP inhibitors and anti-B7H 3 antibodies | 拜耳制药股份公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-108025085-A | Antibody Drug Conjugates (ADCs) of KSP inhibitors and anti-B7H 3 antibodies | 拜耳制药股份公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-106456800-B | IGF-1R antibody-drug-conjugates and uses thereof for the treatment of cancer | 皮埃尔法布雷医药公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-107635586-A | The antibody drug conjugate (ADC) of KSP inhibitor and not glycosyafated anti-TWEAKR antibody | 拜耳医药股份有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-106470708-A | Antibody-drug-conjugates and their use for the treatment of cancer | 皮埃尔法布雷医药公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-106456800-A | IGF-1R antibody-drug-conjugates and uses thereof for the treatment of cancer | 皮埃尔法布雷医药公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104755494-A | Antibody-Drug Conjugates | DAIICHI SANKYO CO LTD | 2015-07-01 | — | — | CN | disclosed |
| CN-1874792-A | Compounds containing matrix metalloproteinase substrates and methods of their use | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2006-12-06 | — | — | CN | disclosed |
| CN-1481377-A | Cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteinases and TNF-alpha | ����˹�ж�-����˹˹����ҩƷ��˾ | 2004-03-10 | — | — | CN | disclosed |