Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.59 |
| ▸ | CES1 | P23141 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27596358 | 1.00 | FAAH (0.59) | FAAHCES1MEN1KMT2ACES2 | |
| Palmitamide SCHEMBL17079324 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL17079411 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Nonanoamide SCHEMBL28509070 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL17079322 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL17079471 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Tetradecanamide SCHEMBL17079414 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Heptanamide SCHEMBL28390014 | 0.98 | FAAH (0.61) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL30164282 | 0.93 | FAAH (0.50) | FAAHCES1MEN1KMT2ACES2 | |
| Trifluoroacetic Acid SCHEMBL27386746 | 0.93 | FAAH (0.50) | FAAHCES1MEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112071-A4 | GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1112071-A1 | GROWTH HORMONE SECRETAGOGUES | Eli Lilly & Company (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000010565-A1 | GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2000-03-02 | — | — | WO | disclosed |
| WO-1999008697-A1 | TREATMENT OF CONGESTIVE HEART FAILURE WITH GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 1999-02-25 | — | — | WO | disclosed |
| WO-1999008699-A1 | GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 1999-02-25 | — | — | WO | disclosed |