SCHEMBL27596382

SCHEMBL27596382

CCOCCOC(=O)C(C#N)C(=O)CC

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
THRB P10828 1/20 0.41
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27578517 0.84 ALDH1A1 (0.52) ALDH1A1TSHRTHRBHSD17B10MEN1
SCHEMBL4370229 0.83 MEN1 (0.40) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL27596386 0.71 LMNA (0.35) ALDH1A1TSHRMEN1KMT2A
SCHEMBL9705616 0.71 MEN1 (0.45) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL12657793 0.70 ALDH1A1 (0.56) ALDH1A1TSHRTHRBHSD17B10
SCHEMBL11510127 0.69 MEN1 (0.38) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL4676252 0.69 ALDH1A1 (0.60) ALDH1A1TSHRTHRBHSD17B10
SCHEMBL10233231 0.69 ALDH1A1 (0.60) ALDH1A1TSHRTHRBHSD17B10
Ethane SCHEMBL20528153 0.69 MEN1 (0.44) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL27479161 0.69 FFAR3 (0.35) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1483320-A Heterocyclic ring contained methylamine cyanoacrylate compound and weeding activity 南开大学 2004-03-24 CN claimed
CN-1483320-A Heterocyclic ring contained methylamine cyanoacrylate compound and weeding activity 南开大学 2004-03-24 CN disclosed