Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25279739 | 0.86 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL29612407 | 0.75 | NOS1 (0.51) | — | |
| SCHEMBL27515794 | 0.75 | NOS1 (0.51) | — | |
| Bromide SCHEMBL7166635 | 0.73 | NOS1 (0.50) | — | |
| SCHEMBL6012026 | 0.69 | TSHR (0.43) | — | |
| SCHEMBL27345425 | 0.68 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL6012027 | 0.68 | KDM4E (0.36) | PDE10AALDH1A1 | |
| SCHEMBL27535194 | 0.68 | PIK3CG (0.41) | — | |
| SCHEMBL12471341 | 0.67 | PDE10A (0.77) | PDE10A | |
| SCHEMBL24506890 | 0.66 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100390174-C | Methylamino-pterin derivative with inhibiting nitric oxide synthetase function | CHINESE PHARMACEUTICAL UNIV (CN) | 2008-05-28 | — | — | CN | disclosed |
| CN-1583746-A | Methylamino-pterin derivative with inhibiting nitric oxide synthetase function | CHINESE PHARMACEUTICAL UNIV (CN) | 2005-02-23 | — | — | CN | disclosed |