Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.65 |
| ▸ | NPC1 | O15118 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581139 | 0.87 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL12994776 | 0.84 | HPGD (0.65) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL27578671 | 0.84 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL27578807 | 0.83 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL30053559 | 0.80 | CA12 (0.73) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL16383911 | 0.79 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL21295380 | 0.78 | CA12 (0.71) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL23977709 | 0.77 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL4123004 | 0.77 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL5788823 | 0.76 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1478771-A | Synthesis method of substituted pyridine carbamide compound | 中国科学院大连化学物理研究所 | 2004-03-03 | — | — | CN | disclosed |