Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 7/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028584 | 0.87 | NCF1 (0.65) | NCF1ADRB2ADRB1NPY5RMAPK1 | |
| SCHEMBL27597792 | 0.86 | NCF1 (0.53) | NCF1ADRB2ADRB1NPY5RKDM4C | |
| SCHEMBL27597796 | 0.86 | NCF1 (0.49) | NCF1ADRB2ADRB1NPY5RMAPK1 | |
| SCHEMBL5022742 | 0.83 | NCF1 (0.48) | NCF1ADRB2ADRB1NPY5RHSD17B10 | |
| SCHEMBL5025401 | 0.81 | NCF1 (0.46) | NCF1HSD17B10LMNAKDM4EMAPT | |
| SCHEMBL5416659 | 0.79 | NCF1 (0.56) | NCF1ADRB2ADRB1NPY5RMAPK1 | |
| SCHEMBL5024416 | 0.79 | NCF1 (0.53) | NCF1ADRB2ADRB1NPY5RMAPK1 | |
| SCHEMBL5412427 | 0.78 | NCF1 (0.59) | NCF1ADRB2ADRB1NPY5RMAPK1 | |
| SCHEMBL6710308 | 0.78 | NCF1 (0.58) | NCF1ADRB2ADRB1NPY5RMAPK1 | |
| SCHEMBL5025361 | 0.76 | NCF1 (0.53) | NCF1ADRB2ADRB1NPY5RMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1627945-A | Quinoline derivatives as NPY antagonists | HOFFMANN LA ROCHE (CH) | 2005-06-15 | — | — | CN | disclosed |