Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 7/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028584 | 0.85 | NCF1 (0.65) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL27597792 | 0.79 | NCF1 (0.53) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL5024416 | 0.79 | NCF1 (0.53) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL27597814 | 0.78 | NCF1 (0.52) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL5411882 | 0.77 | NCF1 (0.64) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL30511704 | 0.76 | NCF1 (0.97) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL5022698 | 0.75 | NCF1 (0.54) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL5025376 | 0.75 | NCF1 (0.57) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL5024569 | 0.74 | NCF1 (0.50) | NCF1ADRB2ADRB1HTTMAPK1 | |
| SCHEMBL5419192 | 0.74 | NCF1 (0.56) | NCF1ADRB2ADRB1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474145-A1 | QUINOLINE DERIVATIVES AS NPY ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066055-A1 | QUINOLINE DERIVATIVES AS NPY ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-14 | — | — | WO | disclosed |