Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 5/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598018 | 0.93 | TDP1 (0.38) | RAB9AMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL27844383 | 0.89 | FLT3 (0.41) | RAB9AALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL27844379 | 0.86 | HTR7 (0.31) | RAB9ATP53TSHRHTR7NPC1 | |
| SCHEMBL27861698 | 0.83 | KMT2A (0.41) | RAB9AMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL27598088 | 0.83 | CYP2A6 (0.36) | RAB9ATP53PKMSMN1; SMN2TSHR | |
| SCHEMBL27598025 | 0.82 | HTR7 (0.30) | HTR7 | |
| SCHEMBL27580438 | 0.81 | MAPT (0.43) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27581431 | 0.81 | KCNH2 (0.38) | RAB9AMAPTALDH1A1HPGDHTR7 | |
| SCHEMBL27598024 | 0.80 | GRM5 (0.36) | PKMHTR7GRM5 | |
| SCHEMBL27861647 | 0.76 | MAPK1 (0.38) | RAB9AMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1458924-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI CO LTD (JP) | 2003-11-26 | — | — | CN | claimed |
| CN-101486683-B | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | Sanitary Material R&D Management Co.,Ltd. (JP) | 2011-12-21 | — | — | CN | disclosed |
| CN-101486683-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-1458924-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI CO LTD (JP) | 2003-11-26 | — | — | CN | disclosed |