Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27861663 | 0.86 | GRIA1 (0.39) | GRM5GRIA1GRIA3PDE4DDRD2 | |
| SCHEMBL27861795 | 0.85 | GAA (0.39) | GRM5FFAR1GRIA1GRIA3PDE4D | |
| SCHEMBL27580424 | 0.85 | MEN1 (0.39) | GRM5FFAR1GRIA1GRIA3PDE4D | |
| SCHEMBL27581432 | 0.85 | GRIA1 (0.39) | GRM5GRIA1GRIA3PDE4DDRD2 | |
| SCHEMBL27598018 | 0.83 | TDP1 (0.38) | GRM5HTR7 | |
| SCHEMBL27861698 | 0.83 | KMT2A (0.41) | HTR7 | |
| SCHEMBL27844382 | 0.83 | DRD2 (0.48) | GRM5FFAR1HTR7DRD2 | |
| SCHEMBL28793687 | 0.81 | TACR3 (0.42) | DRD2 | |
| SCHEMBL27844383 | 0.80 | FLT3 (0.41) | HTR7 | |
| SCHEMBL27598043 | 0.80 | RAB9A (0.34) | GRM5HTR7PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1458924-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI CO LTD (JP) | 2003-11-26 | — | — | CN | claimed |
| CN-101486683-B | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | Sanitary Material R&D Management Co.,Ltd. (JP) | 2011-12-21 | — | — | CN | disclosed |
| CN-101486683-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-1458924-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI CO LTD (JP) | 2003-11-26 | — | — | CN | disclosed |