Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.56 |
| ▸ | ITGAV | P06756 | 10/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.56 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.56 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450086 | 0.83 | HTT (0.51) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6771845 | 0.80 | ITGB3 (0.71) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6779339 | 0.79 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6773037 | 0.78 | ITGB3 (0.65) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL11954569 | 0.76 | TOP2A (0.57) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6800874 | 0.75 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL7377874 | 0.75 | TOP2A (0.53) | ITGB3ITGAVLTA4HALDH1A1 | |
| SCHEMBL25456590 | 0.75 | PLA2G4A (0.56) | ALDH1A1PLA2G4A | |
| SCHEMBL1667448 | 0.75 | PLA2G4A (0.56) | ALDH1A1PLA2G4A | |
| SCHEMBL19119202 | 0.75 | TDP1 (0.60) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1471512-A | Geminally substituted alphavβ3Integrin antagonists | — | 2004-01-28 | — | — | CN | claimed |
| CN-1471512-A | Geminally substituted alphavβ3Integrin antagonists | — | 2004-01-28 | — | — | CN | disclosed |