Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475094 | 0.79 | GPR119 (0.56) | GPR119MAPTSMN1; SMN2DPP4STS | |
| SCHEMBL27572305 | 0.75 | MMP13 (0.51) | GPR119MAPTDPP4STSMMP13 | |
| SCHEMBL27617911 | 0.74 | SLC6A2 (0.40) | MAPTDPP4KDM4EKDM1A | |
| SCHEMBL16818111 | 0.74 | GPR119 (0.52) | GPR119MAPTSMN1; SMN2STSKDM4E | |
| SCHEMBL16825244 | 0.74 | GPR119 (0.60) | GPR119MAPTSMN1; SMN2DPP4STS | |
| SCHEMBL1474825 | 0.74 | GPR119 (0.60) | GPR119MAPTSMN1; SMN2DPP4KDM4E | |
| SCHEMBL20015328 | 0.74 | GPR119 (0.59) | GPR119MAPTSMN1; SMN2DPP4KDM4E | |
| SCHEMBL27599757 | 0.73 | GPR119 (0.46) | GPR119MAPTSMN1; SMN2DPP4STS | |
| SCHEMBL1475476 | 0.73 | GPR119 (0.63) | GPR119MAPTSMN1; SMN2DPP4STS | |
| SCHEMBL22265504 | 0.73 | GPR119 (0.58) | GPR119MAPTSMN1; SMN2DPP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100389113-C | Nitrogen-containing heterocyclic compound and drug containing same | EISAI CO LTD (JP) | 2008-05-21 | — | — | CN | disclosed |
| CN-1630650-A | Nitrogen-containing heterocyclic compound and drug containing same | EISAI CO LTD (JP) | 2005-06-22 | — | — | CN | disclosed |