Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.57 |
| ▸ | NAAA | Q02083 | 2/20 | 0.55 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23627359 | 0.87 | L3MBTL1 (0.73) | L3MBTL1FOLH1NAAAMLYCDCA2 | |
| SCHEMBL24153985 | 0.87 | L3MBTL1 (0.73) | L3MBTL1FOLH1NAAAMLYCDCA2 | |
| SCHEMBL1859906 | 0.85 | MLYCD (0.60) | L3MBTL1NAAAMLYCDHDAC3HDAC1 | |
| SCHEMBL1857658 | 0.85 | MLYCD (0.60) | L3MBTL1NAAAMLYCDHDAC3HDAC1 | |
| SCHEMBL27619619 | 0.85 | EPHX1 (0.58) | L3MBTL1NAAAMLYCDHDAC3HDAC1 | |
| SCHEMBL19022029 | 0.85 | L3MBTL1 (0.71) | L3MBTL1FOLH1NAAAMLYCDCA2 | |
| SCHEMBL18782285 | 0.81 | L3MBTL1 (0.63) | L3MBTL1FOLH1NAAAMLYCDCA2 | |
| SCHEMBL16093023 | 0.80 | L3MBTL1 (0.67) | L3MBTL1NAAAMLYCDHDAC3HDAC1 | |
| SCHEMBL6535660 | 0.79 | L3MBTL1 (0.86) | L3MBTL1FOLH1NAAAMLYCDHDAC3 | |
| SCHEMBL9265536 | 0.79 | L3MBTL1 (0.86) | L3MBTL1FOLH1NAAAMLYCDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |