Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.61 |
| ▸ | BCHE | P06276 | 4/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718542 | 0.84 | NAAA (0.73) | ACHEBCHENAAAHDAC1HDAC3 | |
| SCHEMBL27619607 | 0.84 | NAAA (0.58) | NAAAHDAC1HDAC3 | |
| SCHEMBL27619622 | 0.83 | NPC1 (0.72) | CHRM2NAAAHDAC1HPGDHDAC3 | |
| SCHEMBL5048321 | 0.83 | NAAA (0.53) | ACHEBCHENAAAHDAC1 | |
| SCHEMBL1853858 | 0.81 | NAAA (0.52) | ACHEBCHENAAAHDAC1HTT | |
| SCHEMBL5044057 | 0.81 | EPHX2 (0.55) | NAAAHDAC1HDAC3 | |
| SCHEMBL27601039 | 0.81 | NAAA (0.63) | NAAAHDAC1HTTHPGDHDAC3 | |
| SCHEMBL1858193 | 0.81 | HDAC3 (0.54) | NAAAHDAC1HDAC3 | |
| SCHEMBL5044018 | 0.80 | NAAA (0.53) | ACHEBCHENAAAHDAC1HDAC3 | |
| SCHEMBL5044262 | 0.80 | L3MBTL1 (0.62) | NAAAHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |