SCHEMBL27601397

SCHEMBL27601397

COC(=O)Oc1c(Cl)cc(Br)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
ALDH1A1 P00352 4/20 0.40
HSD17B10 Q99714 3/20 0.40
KDM4E B2RXH2 3/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.38
CUL4A Q13619 2/20 0.38
HPGD P15428 4/20 0.37
TPMT P51580 1/20 0.36
GPR35 Q9HC97 1/20 0.36
TSHR P16473 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17355772 0.86 KDM4E (0.41) POLBALDH1A1HSD17B10KDM4EGAA
SCHEMBL19546119 0.84 ALDH1A1 (0.42) ALDH1A1KDM4EGAACUL4AHPGD
SCHEMBL27601386 0.80 HSD17B10 (0.52) ALDH1A1HSD17B10KDM4EGAACUL4A
SCHEMBL4641540 0.80 POLB (0.43) POLBALDH1A1HSD17B10KDM4EGAA
SCHEMBL28740318 0.79 TPMT (0.59) POLBALDH1A1HSD17B10KDM4EGAA
SCHEMBL14628855 0.79 PPARA (0.47) POLBALDH1A1KDM4EGAAHPGD
SCHEMBL17356411 0.77 MAPK1 (0.52) ALDH1A1KDM4EMAPK1GPR35MEN1
SCHEMBL4641535 0.76 POLB (0.40) POLBALDH1A1HSD17B10KDM4EHPGD
SCHEMBL4644362 0.76 POLB (0.40) POLBALDH1A1HSD17B10KDM4EGAA
SCHEMBL4642320 0.73 POLB (0.38) POLBALDH1A1KDM4EGAAGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed