SCHEMBL4644362

SCHEMBL4644362

C[CH]C(=O)Oc1c(Cl)cc(Br)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
NMT1 P30419 1/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 3/20 0.33
HSD17B10 Q99714 1/20 0.33
KMT2A Q03164 4/20 0.32
MEN1 O00255 3/20 0.32
TSHR P16473 2/20 0.32
GPR35 Q9HC97 1/20 0.32
TPMT P51580 1/20 0.32
GAA P10253 1/20 0.32
MAPK1 P28482 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643493 0.91 HSD17B10 (0.40) POLBALDH1A1KDM4EHSD17B10KMT2A
SCHEMBL4641643 0.85 CA1 (0.38) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL4642201 0.81 HSD17B10 (0.46) HSD17B10KMT2AMEN1TSHRTPMT
SCHEMBL4642406 0.81 POLB (0.38) POLBNMT1ALDH1A1KDM4EKMT2A
SCHEMBL4641540 0.79 POLB (0.43) POLBNMT1ALDH1A1KDM4EHSD17B10
SCHEMBL4644487 0.78 POLB (0.36) POLBALDH1A1KDM4EKMT2AMEN1
SCHEMBL27601397 0.76 POLB (0.41) POLBALDH1A1KDM4EHSD17B10KMT2A
SCHEMBL4641535 0.75 POLB (0.40) POLBNMT1ALDH1A1KDM4EHSD17B10
SCHEMBL4642631 0.74 KMT2A (0.34) POLBALDH1A1KDM4EKMT2AMEN1
SCHEMBL4642286 0.74 HSD17B10 (0.37) POLBALDH1A1KDM4EHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed