Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL11134409 | 0.91 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Phenol SCHEMBL3671181 | 0.82 | SRC (0.44) | ALDH1A1CA12CA1CA2CA4 | |
| Phenol SCHEMBL27821795 | 0.81 | SRC (0.43) | CA12CA1CA2CA4CA9 | |
| Naphthalene SCHEMBL5839060 | 0.80 | SRC (0.44) | ALDH1A1HPGDSRCTSHR | |
| Benzoic Acid SCHEMBL27368106 | 0.80 | TSHR (0.47) | ALDH1A1NAPRTHSD17B10SRCTSHR | |
| Salicylic Acid SCHEMBL4295686 | 0.78 | KDM4E (0.82) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL31490109 | 0.78 | KDM4E (0.82) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| SCHEMBL18141518 | 0.78 | SRC (0.42) | KDM4EALDH1A1SRCTSHR | |
| Aniline SCHEMBL2803039 | 0.78 | POLB (0.44) | SMN1; SMN2LMNASRCTSHRMEN1 | |
| Naphthalene SCHEMBL15322158 | 0.78 | SRC (0.42) | ALDH1A1HPGDSRCTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102352206-A | Pressure-sensitive adhesive for polaroid | YANTAI DARBOND ELECTRONICS MATERIALS CO LTD | 2012-02-15 | — | — | CN | claimed |
| CN-102352206-A | Pressure-sensitive adhesive for polaroid | YANTAI DARBOND ELECTRONICS MATERIALS CO LTD | 2012-02-15 | — | — | CN | disclosed |
| CN-100427543-C | Acrylic acid polymer powder, acrylic acid sol and forming article | KURARAY CO (JP) | 2008-10-22 | — | — | CN | disclosed |
| CN-1517400-A | Acrylic acid polymer powder, acrylic acid sol and forming article | 株式会社可乐丽 | 2004-08-04 | — | — | CN | disclosed |