Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.82 |
| ▸ | HPGD | P15428 | 7/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | CA1 | P00915 | 2/20 | 0.82 |
| ▸ | CA2 | P00918 | 2/20 | 0.82 |
| ▸ | CA12 | O43570 | 1/20 | 0.82 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.82 |
| ▸ | CA4 | P22748 | 1/20 | 0.82 |
| ▸ | CA6 | P23280 | 1/20 | 0.82 |
| ▸ | CA7 | P43166 | 1/20 | 0.82 |
| ▸ | CA9 | Q16790 | 1/20 | 0.82 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.82 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL31490109 | 1.00 | KDM4E (0.82) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL28820609 | 0.98 | KDM4E (0.78) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL8176134 | 0.98 | KDM4E (0.78) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL28303438 | 0.94 | KDM4E (0.72) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL30940555 | 0.91 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9228055 | 0.91 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9800701 | 0.91 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL11514985 | 0.91 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6725453 | 0.91 | KDM4E (0.75) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL8433746 | 0.91 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115104603-A | Oil suspending agent additive and preparation method thereof | 威尔（福建）生物有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-110234636-B | Compositions comprising methylphenidate prodrugs, methods of making and using the same | 坎普哈姆公司 | 2022-09-20 | — | — | CN | claimed |
| CN-110234636-A | Composition comprising methylphenidate prodrug, method of manufacture and use thereof | 坎普哈姆公司 | 2019-09-13 | — | — | CN | claimed |
| CN-118255636-A | Plant nutrient solution for water planting and application thereof | 中国农业科学院都市农业研究所 | 2024-06-28 | — | — | CN | disclosed |
| US-20230416935-A1 | SINGLE-ATOMICALLY DISPERSED METAL / UNCONVENTIONAL-PHASE TRANSITION-METAL DICHALCOGENIDE NANOSHEET HYBRIDS AND METHODS OF PREPARATION AND USE THEREOF | CITY UNIVERSITY OF HONG KONG (CN) | 2023-12-28 | — | — | US | disclosed |
| CN-116003181-A | Hydroponic nutrient solution and application thereof | 京东方后稷科技(北京)有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115974612-A | Plant nutrient solution and application thereof | 中国农业科学院都市农业研究所 | 2023-04-18 | — | — | CN | disclosed |
| CN-113956635-B | Biodegradable polyester composition and application thereof | 东莞市金富亮塑胶科技有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-108289697-B | Scoring balloon with translating score line | 巴德股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-115104603-A | Oil suspending agent additive and preparation method thereof | 威尔（福建）生物有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-110234636-B | Compositions comprising methylphenidate prodrugs, methods of making and using the same | 坎普哈姆公司 | 2022-09-20 | — | — | CN | disclosed |
| US-20090300790-A1 | Shine clade of transcription factors and their use | STICHTING WAGENINGEN RESEARCH (NL) | 2009-12-03 | — | — | US | disclosed |
| CN-100416415-C | Charge control resin particle and toner for electrostatic development | TOKATA KAGAKU KOGYO K K (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-100395539-C | Rapid detecting box for vegetable nitrate content, its detecting reagent and microsampling needle | SHANQUAN ZHANG (CN) | 2008-06-18 | — | — | CN | disclosed |
| US-20070292501-A1 | CHEWABLE SOFT GELATIN CAPSULES | SOFT GEL TECHNOLOGIES, INC. | 2007-12-20 | — | — | US | disclosed |
| WO-2007143652-A2 | CHEWABLE SOFT GELATIN CAPSULES | SOFT GEL TECHNOLOGIES, INC. (US) | 2007-12-13 | — | — | WO | disclosed |
| CN-1983044-A | Charge control agent, charge control resin particles and toner for developing electrostatic images | ORIENT CHEMICAL IND (JP) | 2007-06-20 | — | — | CN | disclosed |
| CN-1645113-A | Rapid detecting box for vegetable nitrate content, its detecting reagent and microsampling needle | ZHANG SHANQUAN (CN) | 2005-07-27 | — | — | CN | disclosed |
| CN-1424629-A | Charge control agent, method for producing same, charge control resin particle, and toner for electrostatic image development | TOKATA KAGAKU KOGYO K K (JP) | 2003-06-18 | — | — | CN | disclosed |
| US-6027746-A | ORAL DRUG DELIVERY SYSTEM COMPRISING A LIQUID PHARMACEUTICAL SUSPENSION OF AN UNPLEASANT TASTING DRUG AND AN ABSORBER PARTICLE (A SILICA) DISPERSED IN AN AQUEOUS OR NONAQUEOUS CARRIER SOLVENT ENCAPSULATED IN A SOFT GELATIN CAPSULE | WARNER-LAMBERT COMPANY (US) | 2000-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070292501-A1 | CHEWABLE SOFT GELATIN CAPSULES | GMPS, PIGS, GYS1 | KDM4E 1525/4885ALDH1A1 3434/4885HPGD 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.