SCHEMBL27601746

SCHEMBL27601746

CC(C)[C@H](N)C(=O)OC(=O)[C@@H](N)CCCNC(N)=O

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 3/20 0.37
OTC P00480 1/20 0.34
ANPEP P15144 2/20 0.33
RNPEP Q9H4A4 2/20 0.33
DNPEP Q9ULA0 1/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
DDAH1 O94760 1/20 0.33
RRM1 P23921 1/20 0.32
ARG1 P05089 1/20 0.32
C3AR1 Q16581 1/20 0.32
SLC15A1 P46059 1/20 0.31
DPP4 P27487 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
NPY1R P25929 1/20 0.30
NPY4R P50391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL25356044 0.98 DPP7 (0.36) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL29106719 0.89 DPP7 (0.41) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL3133848 0.89 DPP7 (0.41) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL27926299 0.88 NPY4R (0.39) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL4586463 0.88 NPY4R (0.39) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL28111481 0.87 DPP7 (0.40) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL28427934 0.84 DPP7 (0.35) DPP7OTCANPEPRNPEPDNPEP
SCHEMBL22160895 0.83 GNAI3 (0.42) DPP7OTCGNAI3GNAO1GNAI1
SCHEMBL27866150 0.83 GNAI3 (0.42) DPP7OTCGNAI3GNAO1GNAI1
SCHEMBL21122142 0.81 DPP7 (0.36) DPP7OTCGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113195487-A 2, 3-diaminosuccinyl conjugate linkers 杭州多禧生物科技有限公司 2021-07-30 CN claimed
CN-106749665-B Conjugates of CC-1065 analogs and bifunctional linkers 辛塔佳有限公司 2021-03-26 CN claimed
CN-106466485-A A kind of targeting ligand-drug coupling body with cell endocytic mediation function 同宜医药开曼有限公司 2017-03-01 CN claimed
CN-103118679-B Conjugates of CC-1065 Analogs and Bifunctional Linkers SYNTARGA B.V. (NL) 2016-12-14 CN claimed
CN-103118679-A Novel conjugates of CC-1065 analogs and bifunctional linkers SYNTARGA BV 2013-05-22 CN claimed
CN-100522249-C Elongated multiple spacers in activatable prodrugs SINTAGAR B V (NL) 2009-08-05 CN claimed
CN-101415679-A Water-soluble CC-1065 analogs and conjugates thereof SINTAGAR B V (NL) 2009-04-22 CN claimed
CN-1511044-A Elogated and multiple spacers in activatible prodrugs 2004-07-07 CN claimed
CN-118613484-A Antifolate linker-drug and antibody-drug conjugates 拜奥迪斯私人有限公司 2024-09-06 CN disclosed
CN-117794581-A Conjugates comprising phosphoantigen and their use in therapy 拜奥迪斯私人有限公司 2024-03-29 CN disclosed
CN-116617410-A AXL-specific antibody drug conjugates for cancer treatment 根马布股份公司 2023-08-22 CN disclosed
CN-116209476-A Antifolate linker-drug and antibody-drug conjugates 拜奥迪斯私人有限公司 2023-06-02 CN disclosed
CN-114621347-A Antibodies that bind AXL 根马布股份公司 2022-06-14 CN disclosed
CN-109963833-B Process for the preparation of mono-protected alpha, omega-diaminoalkanes 拜奥迪斯私人有限公司 2022-02-22 CN disclosed
CN-106749665-B Conjugates of CC-1065 analogs and bifunctional linkers 辛塔佳有限公司 2021-03-26 CN disclosed
CN-103118679-B Conjugates of CC-1065 Analogs and Bifunctional Linkers SYNTARGA B.V. (NL) 2016-12-14 CN disclosed
CN-105899235-A Method for purifying CYS-linked antibody-drug conjugates 斯索恩生物制药有限公司 2016-08-24 CN disclosed
CN-103118679-A Novel conjugates of CC-1065 analogs and bifunctional linkers SYNTARGA BV 2013-05-22 CN disclosed
CN-100522249-C Elongated multiple spacers in activatable prodrugs SINTAGAR B V (NL) 2009-08-05 CN disclosed
CN-101415679-A Water-soluble CC-1065 analogs and conjugates thereof SINTAGAR B V (NL) 2009-04-22 CN disclosed