Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.39 |
| ▸ | NPY1R | P25929 | 6/20 | 0.39 |
| ▸ | NPY2R | P49146 | 4/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | OTC | P00480 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926299 | 1.00 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL3898461 | 0.90 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL28712062 | 0.89 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL288133 | 0.89 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL9237239 | 0.89 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL27601746 | 0.88 | DPP7 (0.37) | NPY4RNPY1RDPP7OTCGNAI3 | |
| SCHEMBL1821005 | 0.88 | NPY4R (0.40) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| Hydrochloric Acid SCHEMBL8040222 | 0.88 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| Hydrochloric Acid SCHEMBL8039440 | 0.88 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL6241648 | 0.88 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085862-A4 | METHOD OF TREATING AN AUTOIMMUNE DISORDER | BRYAN THOMAS B (US) | 2008-07-23 | — | — | EP | claimed |
| EP-1085862-A1 | METHOD OF TREATING AN AUTOIMMUNE DISORDER | Bryan, Thomas B. (US) | 2001-03-28 | — | — | EP | claimed |
| WO-1999065479-A1 | METHOD OF TREATING AN AUTOIMMUNE DISORDER | BRYAN THOMAS B (US) | 1999-12-23 | — | — | WO | claimed |
| EP-3348578-B1 | DOUBLE-TARGET MUTEIN MUR6S4TR OF TRAIL, AND PREPARATION METHOD AND USE THEREOF | CHENGDU HUACHUANG BIOTECHNOLOGY CO LTD (CN) | 2019-10-09 | — | — | EP | disclosed |
| EP-3348578-A1 | DOUBLE-TARGET MUTEIN MUR6S4TR OF TRAIL, AND PREPARATION METHOD AND USE THEREOF | Chengdu Huachuang Biotechnology Co., Ltd (CN) | 2018-07-18 | — | — | EP | disclosed |
| US-20180170993-A1 | Bi-targeted Mutain MuR6S4TR of TRAIL and Preparation Method and Application Thereof | CHENGDU HUACHUANG BIOTECHNOLOGY CO., LTD (CN) | 2018-06-21 | — | — | US | disclosed |
| EP-3145524-A2 | SYNTHESIS OF BETA-ARRESTIN EFFECTORS | Trevena, Inc. (US) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015179349-A2 | SYNTHESIS OF BETA-ARRESTIN EFFECTORS | TREVENA, INC. (US) | 2015-11-26 | — | — | WO | disclosed |
| CN-103249428-A | Application of calcineurin inhibitor 1 in preparation of drugs for treating diseases related to NF-kB activity increase | MACLEE TECHNOLOGY INC | 2013-08-14 | — | — | CN | disclosed |
| EP-1526179-B9 | Method for producing l-amino acid using bacteria belonging to the genus escherichia | AJINOMOTO KK (JP) | 2007-10-10 | — | — | EP | disclosed |
| EP-1526179-B1 | Method for producing l-amino acid using bacteria belonging to the genus escherichia | AJINOMOTO KK (JP) | 2007-05-02 | — | — | EP | disclosed |
| EP-0274267-B1 | COSMETIC PRODUCT | UNILEVER PLC (GB) | 1992-07-22 | — | — | EP | disclosed |
| EP-0274267-A1 | Cosmetic product | UNILEVER PLC (GB) | 1988-07-13 | — | — | EP | disclosed |