Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 3/20 | 0.38 |
| ▸ | ARG2 | P78540 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620512 | 0.94 | GGT1 (0.39) | MAPTGGT1ARG1ARG2GRM2 | |
| SCHEMBL27620489 | 0.94 | GGT1 (0.39) | MAPTGGT1ARG1ARG2NOS1 | |
| SCHEMBL27601891 | 0.92 | METAP1 (0.41) | MAPTGGT1ARG1ARG2GRM2 | |
| SCHEMBL27620466 | 0.87 | GGT1 (0.41) | MAPTGGT1ARG1ARG2BLM | |
| SCHEMBL27601847 | 0.85 | MAPT (0.40) | MAPTGGT1ARG1ARG2BLM | |
| SCHEMBL27620531 | 0.81 | GGT1 (0.39) | MAPTGGT1ARG1ARG2BLM | |
| SCHEMBL27601905 | 0.81 | GGT1 (0.39) | GGT1ARG1ARG2GRM2GRM3 | |
| SCHEMBL28752258 | 0.81 | GGT1 (0.39) | MAPTGGT1ARG1ARG2GRM2 | |
| SCHEMBL4335456 | 0.80 | GGT1 (0.50) | MAPTGGT1ARG1ARG2BLM | |
| SCHEMBL27602074 | 0.80 | GGT1 (0.50) | MAPTGGT1ARG1ARG2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | claimed |
| CN-100462351-C | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2009-02-18 | — | — | CN | disclosed |
| CN-1856301-A | Curable beta-amino acid | WARNER LAMBERT CO (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | disclosed |