Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 2/20 | 0.36 |
| ▸ | ARG2 | P78540 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620512 | 0.97 | GGT1 (0.39) | GGT1MAPTARG1ARG2METAP1 | |
| SCHEMBL27601891 | 0.95 | METAP1 (0.41) | GGT1MAPTARG1ARG2METAP1 | |
| SCHEMBL27601895 | 0.94 | MAPT (0.42) | GGT1MAPTARG1ARG2METAP1 | |
| SCHEMBL28752258 | 0.88 | GGT1 (0.39) | GGT1MAPTARG1ARG2GRM2 | |
| SCHEMBL27620435 | 0.86 | METAP1 (0.36) | GGT1MAPTARG1ARG2METAP1 | |
| SCHEMBL27601905 | 0.84 | GGT1 (0.39) | GGT1ARG1ARG2GRM2GRM3 | |
| SCHEMBL27620521 | 0.83 | GGT1 (0.38) | GGT1ARG1ARG2GRM2GRM3 | |
| SCHEMBL28755080 | 0.83 | METAP1 (0.39) | GGT1MAPTMETAP1METAP2GRM2 | |
| SCHEMBL27601866 | 0.82 | GGT1 (0.37) | GGT1MAPTARG1ARG2METAP1 | |
| SCHEMBL27620501 | 0.81 | GGT1 (0.47) | GGT1MAPTARG1ARG2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | claimed |
| CN-100462351-C | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2009-02-18 | — | — | CN | disclosed |
| CN-1856301-A | Curable beta-amino acid | WARNER LAMBERT CO (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | disclosed |