Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995200 | 0.79 | ALDH1A1 (0.53) | KMT2AMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6652692 | 0.78 | ALDH1A1 (0.38) | KMT2AMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL5258714 | 0.75 | MAPT (0.66) | KMT2AATMMAPTKDM4EPOLB | |
| SCHEMBL724222 | 0.75 | LTA4H (0.47) | KMT2AATMMAPTKDM4EALDH1A1 | |
| SCHEMBL29111812 | 0.73 | KMT2A (0.46) | KMT2AATMMAPTKDM4EPOLB | |
| SCHEMBL27754289 | 0.71 | KMT2A (0.44) | KMT2AATMMAPTKDM4EPOLB | |
| SCHEMBL21722722 | 0.71 | POLB (0.67) | KMT2AATMMAPTKDM4EPOLB | |
| SCHEMBL27935860 | 0.71 | KDM4E (0.44) | KMT2AATMMAPTKDM4EPOLB | |
| SCHEMBL69204 | 0.70 | — | — | |
| SCHEMBL22134230 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100540538-C | High Conductivity Calcium-Activated K Channel Opener | TANABE SEIYAKU CO (JP) | 2009-09-16 | — | — | CN | disclosed |
| CN-1503786-A | High Conductivity Calcium-Activated K Channel Opener | ������ҩ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |